As research into Endometriosis is gathering pace, it’s maybe worth having a look at some of the suggested reasons for endometriosis. At the moment there is still no definitive answer, indeed there may be more than one cause – or a combination of causes. One of the most promising theories is genetic. There is extensive evidence that families where one person has endometriosis have a propensity for other female members to have this. The biggest problem with this theory is that the actual cause is not explained. Some families appear to have a high percentage of Endometriosis sufferer’s, whereas other …continue reading
No one knows why people get endo, or what causes it. Perhaps one day these questions will have answers. Until then, research on endometriosis needs to continue to be done. Research is underway in several centres across the world looking for genes that may make people susceptable to endometriosis, if successful this may well hold the key to a cure or even a test to see if someone will get it in the near future!
Source: Human Reproduction 2003; 18: 985–9 Human leukocyte antigen (HLA) systems may be involved in the etiology of endometriosis, indicates research conducted in Japan. HLA genes have already been implicated in insulin-dependent diabetes mellitus, systemic lupus erythematosus, and pre-eclampsia, and women with endometriosis have higher rates of autoimmune and other chronic diseases than do women in the general population. To investigate the possibility of an autoimmune contribution to endometriosis, Keisuke Ishii (Niigata University School of Medicine, Japan) and co-workers genotyped 83 women with a laparoscopic diagnosis of the condition, looking specifically for the HLA-DQB1 and HLA-DBP1 alleles. Ishii et al …continue reading