i was diagnosed with endometriosis on march 17 2005. my doctor started my lupron shots after my laproscopy and the side effects have been pretty horendous. i was just wondering if anyone else has had some problems with the shot. not long after my first shot i developed hot flashes, mood swings, leg pains, severe depression, anxiety and really bad insomnia. its just been pretty difficult to deal with all around. im pretty much pain free for now but the after effects have been hard on me.